Tomato Spotted Wilt Virus (TSWV)

Tomato Spotted Wilt Virus

Tomato spotted wilt virus (TSWV) is a negative-sense RNA virus composed of three negative-sense single-stranded RNA (ssRNA) species, L, M, and S. Like other members of the Bunyaviridae family, the TSWV virion is enveloped and spherical in shape. TSWV is one of the most economically destructive plant viruses, causing severe damage to cash crops. TSWV is cyclically transmitted by at least 10 different species of thrips^[1].

References:

[1]. Jia Li, et al. Structure and Function Analysis of Nucleocapsid Protein of Tomato Spotted Wilt Virus Interacting with RNA Using Homology Modeling. J Biol Chem. 2014 Dec 24;290(7):3950–3961.

Tomato Spotted Wilt Virus (TSWV) Inhibitor (1)

Tomato Spotted Wilt Virus (TSWV) Related Products (1):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-168999

TSWV-IN-2	Inhibitor
TSWV-IN-2 (Compound Z9) is an inhibitor of TSWV N protein, with an EC₅₀ of 65.3 μg/mL against TSWV. TSWV-IN-2 has broad-spectrum antiviral activity against plant viruses. TSWV-IN-2 targets the TSWV N protein, interferes with the formation of condensates between the N protein and RNA, and inhibits the replication of viral ribonucleoproteins.

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